June 24, 2025
Vaccines reduce the spread of drug-resistant infections and antibiotic use.
Typhoid Conjugate Vaccine (TCV)
- Typhoid fever is endemic in Nepal. Typhoid vaccination is a cost-effective strategy to substantially decrease its incidence and help combat AMR.
- Included in the immunization program: 1 dose at 15 months
- Modeling estimates indicate potential aversion of 68 to 70 percent of drug-resistant typhoid fever cases when implemented along with a 15-year catch-up campaign.
Pneumococcal Conjugate Vaccine (PCV)
- Acute otitis media (AOM) and invasive pneumococcal disease (IPD) are acute respiratory illnesses associated with Streptococcus pneumoniae infections.
- Vaccine included in the immunization program: 3 doses – 6 weeks, 10 weeks, and 9 months
- PCV is projected to avert 55.7 percent of AOM and 80.8 percent of IPD antibiotic-treated cases.
Rotavirus Vaccine
- Rotavirus infections are a leading cause of severe diarrhea in children under five years old, with many requiring hospitalization.
- Included in the immunization programme: 2 doses at 6 weeks and 10 weeks
- Rotavirus vaccines are predicted to avert 55.6 percent of the total antibiotic-treated cases of rotavirus-attributable diarrhea in Nepal.
Maternal K. Pneumoniae Vaccine
- Klebsiella pneumoniae is a critical-priority pathogen and a leading cause of neonatal sepsis in Nepal.
- There are no licensed vaccines in the immunization program.
- A maternal vaccine providing protection to newborns could prevent 2,273 sepsis cases and 456 sepsis deaths in neonates.
Read the brief here.
