The Question

Given that there is a “post-antibiotic effect” associated with antibiotic administration, can longer intervals between doses help to combat antimicrobial resistance?

What we found

Longer post-antibiotic effects do not necessarily promote longer interval times.

Why it matters

Studying phenomena like the post-antibiotic effect has important implications for optimizing antibiotic dosing regimens to treat bacterial infections as well as minimize antibiotic resistance.