In a cross-sectional study co-authored by CDDEP Senior Fellow Eili Klein, researchers identified a high prevalence of resistance in extended-spectrum beta-lactamase (ESBL)-producing organisms among patients with clinical features of healthcare-associated infections (HAIs) at an urban tertiary hospital in Sierra Leone. Resistance rates were highest among all ESBL-producing organisms (58 percent), followed by carbapenem-resistant non-lactose fermenting gram-negative bacilli (13.4 percent), carbapenem-resistant Acinetobacter baumannii(8.7 percent), and carbapenem-resistant Enterobacteriaceae(CRE) (1.3 percent). All Staphylococcus aureus isolates in the study were resistant to methicillin.