May 27, 2010
![](https://onehealthtrust.org/wp-content/uploads/2017/06/geli.2009.modeling_the_mechanism_of_postantibiotic_effect_and_determining_implications_for_dosing_regimens_7.jpg)
The Question
Given that there is a “post-antibiotic effect” associated with antibiotic administration, can longer intervals between doses help to combat antimicrobial resistance?
What we found
Longer post-antibiotic effects do not necessarily promote longer interval times.
Why it matters
Studying phenomena like the post-antibiotic effect has important implications for optimizing antibiotic dosing regimens to treat bacterial infections as well as minimize antibiotic resistance.